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目的分析夫精宫腔内人工授精妊娠结局及子代安全性。方法分析2008年1月~2012年12月行夫精宫腔内人工授精后临床妊娠的的103个周期,随访妊娠结局至产后1年。结果异位妊娠率1.94%,自然流产率16.50%,多胎率2.91%,早产率2.38%,剖宫产率72.62%。自然流产组与正常宫内孕组比较女方年龄、自然流产史有差异(P<0.05)。新生儿男女性别比为1.56,平均出生体重、身长均在正常范围,无出生缺陷,1岁时仅1例体重偏轻。结论夫精宫腔内人工授精多胎率、剖宫产率高,自然流产与患者年龄、自然流产史有关,出生后子代发育正常,男性明显多于女性。
Objective To analyze the pregnancy outcomes and safety of offspring of intrauterine insemination in Fufang. Methods 103 cycles of clinical pregnancy after intrauterine insemination from January 2008 to December 2012 were analyzed. The pregnancy outcome was followed up to 1 year after delivery. Results The rate of ectopic pregnancy was 1.94%, spontaneous abortion rate was 16.50%, multiple birth rate was 2.91%, premature birth rate was 2.38% and cesarean section rate was 72.62%. The spontaneous abortion group compared with the normal intrauterine pregnancy group women’s age, spontaneous abortion history difference (P <0.05). Neonatal gender ratio of 1.56, the average birth weight, height are in the normal range, no birth defects, only 1 case of 1-year-old body weight. Conclusion Fufang intrauterine artificial insemination rate of multiple births, cesarean section rate, spontaneous abortion and patient age, history of spontaneous abortion, normal offspring after birth, male significantly more than women.