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近几年深入研究得出了惊人的结果:约96％十二指肠溃疡和约70％胃溃疡应做为感染性疾病采观察。老的观点“无酸—无溃疡”扩展为“无酸或无幽门螺杆菌—无溃疡”根据这个结论,最常见多发胃十二指肠溃疡通过一段时间治疗是可以长期治愈的,众多深入研究明确指出:治愈幽螺杆菌感染可以进一步完全修复胃十二指肠溃疡底部粘膜从而加速治愈溃疡。首先是使对治疗不敏感的溃疡治愈,特别是在根除幽门螺杆菌后消化性溃疡稳定缓解,溃疡复发率几乎为零。相比之下幽门螺杆菌阻性的胃溃疡复发率为50％,十二指肠溃疡复发率70％～90％。并且在根除幽门螺杆菌后能减少溃疡并发症。对初发的胃十二指肠溃疡是否应该抗菌治疗仍有争议(表1)。
In recent years, in-depth studies have yielded surprising results: about 96% of duodenal ulcers and about 70% of gastric ulcers should be taken as an infectious disease. The old notion of “no acid-no ulcer” expands to “acid-free or non-Helicobacter pylori-no ulcer.” Based on this conclusion, the most common multi-gastroduodenal ulcer can be cured over a period of time, and numerous in-depth studies Clearly pointed out that: cure H. pylori infection can further completely repair the bottom of gastric ulcer mucosa to accelerate the healing of ulcers. The first is to cure the ulcer that is not sensitive to treatment, especially the stabilization of peptic ulcer after eradication of Helicobacter pylori. The ulcer recurrence rate is almost zero. In contrast, H. pylori resistance gastric ulcer recurrence rate was 50%, duodenal ulcer recurrence rate of 70% to 90%. And to eradicate Helicobacter pylori can reduce ulcer complications. Whether debilitating gastroduodenal ulcer should be antimicrobial treatment is still controversial (Table 1).