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目的 :探讨大肠癌区域淋巴结转移规律及术中判断淋巴结是否转移的准确性。方法 :对 170例可根治性大肠癌的手术标本常规病理切片诊断 ,分析淋巴结转移情况。结果 :大肠癌淋巴结阳性率、转移度与患者性别、年龄和肿瘤大小无明显关系 ,而与肿瘤部位、浸润深度有关 ,直肠癌或肿瘤浸润至肠壁外时 ,其淋巴结阳性率和淋巴结转移度显著高于结肠癌或肿瘤局限于肠壁内者 (P <0 0 5 ) ,淋巴结转移度和肿瘤细胞分化程度有关。 86例术中探及淋巴结肿大 ,84例未及肿大 ,术后证实分别有 5 6例和 46例淋巴结转移阳性。结论 :大肠癌淋巴结转移与肿瘤部位、浸润深度及分化程度有关 ,术中判断淋巴结是否转移并不准确 ,应常规作区域淋巴结清扫。
Objective: To investigate the regional lymph node metastasis of colorectal cancer and the accuracy of intraoperative lymph node metastasis. Methods: Routine pathological diagnosis was performed on surgical specimens of 170 patients with curable colorectal cancer, and lymph node metastasis was analyzed. RESULTS: The positive rate and metastasis of lymph node in colorectal cancer were not significantly related to the patient’s gender, age and tumor size, but related to the tumor site and depth of invasion. When the colorectal cancer or tumor infiltrated into the outside of the intestine, the lymph node positive rate and lymph node metastasis were related. Significantly higher than colon cancer or tumors confined to the intestinal wall (P < 0.05), the degree of lymph node metastasis and the degree of differentiation of tumor cells. Intraoperative exploration of 76 cases and lymphadenopathy, 84 cases were not enlarged, postoperatively confirmed 56 cases were positive and 46 cases of lymph node metastasis. Conclusion : Lymph node metastasis of colorectal cancer is related to tumor location, depth of invasion, and differentiation. It is inaccurate to determine lymph node metastasis during operation. Regional lymph node dissection should be routinely performed.