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全肠道外营养(Total parenteral nutrition,TPN)是过去10多年间外科领域中的重大进展之一。非蛋白质热卡源起初几乎均由葡萄糖提供,以后发现高糖有明显副作用,如导致糖代谢紊乱、高渗障碍等,由于用脂肪代替部分葡萄糖可提高TPN的营养效果,从而促进了脂肪乳剂的发展。静脉脂肪乳剂有下列优点:①容量小而含热量高,每克脂肪可提供gKcal热量;②等渗;③代谢如同正常的外源和同源性脂肪;④提供必需脂肪酸;⑤能使机体脂肪成分维持正常;⑥在尿和粪中不丢失;⑦可经周围静脉输入。对外科代谢的深入研究表明,创伤、感染等应激时,由于胰岛素清除加快及阻抗状态的存在,葡萄糖的利用发生障碍,使机体缺少能源,
Total parenteral nutrition (TPN) is one of the major advances in the surgical field over the past 10 years. Non-protein heat card source initially provided almost by glucose, and later found that high glucose has obvious side effects, such as leading to glucose metabolism disorders, hyperosmolar disorders, etc., as part of the fat instead of glucose can increase the nutritional effect of TPN, thereby promoting the fat emulsion development of. Intravenous fat emulsion has the following advantages: ① small capacity and high calorie content, gKcal calories per gram of fat available; ② isotonic; ③ metabolism as normal exogenous and homologous fat; ④ provide essential fatty acids; ⑤ body fat Ingredients remain normal; ⑥ not lost in urine and feces; ⑦ can be imported through the peripheral vein. In-depth study of surgical metabolism shows that, trauma, infection and other stress, due to the accelerated insulin clearance and the presence of impedance status, glucose utilization disorders occur, the body lacks energy,