论文部分内容阅读
育龄期女性,临床表现多系统损害、自身抗体阳性、补体下降,同时血免疫固定电泳见游离λ轻链单克隆条带;肾脏损害表现尿检异常伴血清肌酐升高,肾活检证实为肾脏淀粉样变性(AL型);皮肤脂肪组织、骨髓活检均示淀粉样变性。最终诊断自身免疫性疾病合并原发性系统性淀粉样变性(累及肾脏、皮肤、心脏、骨髓)。
Childbearing age women, clinical manifestations of multiple system damage, autoantibodies positive, decreased complement, while immune fixed electrophoresis of free lambda light chain monoclonal bands; renal damage showed abnormal urine test with serum creatinine, renal biopsy confirmed as amyloidosis Degeneration (AL type); skin adipose tissue, bone marrow biopsy showed amyloidosis. The final diagnosis of autoimmune diseases combined with primary systemic amyloidosis (involving the kidney, skin, heart, bone marrow).