论文部分内容阅读
BACKGROUND: Intracerebral hemorrhage(ICH) and coronary heart disease (CHD) have the same pathological base, atherosclerosis, and the similar risk factors, such as smoking ,drinking, hypertension,hyperlipemia, diabetes mellitus, etc; but the distributions of two diseases are very different in the populations.This may be related to the exposure of risk factors and different effects of risk factors on two diseases.OBJECTIVE: To analyze the distribution difference of risk factors for ICH and CHD in the populations of Tongliao city of Nei Monggol Autonomous Region.DESIGN: Retrospective analysis.SETTING: School of Radiation Medicine and Public Health, Soochow University; Tongliao Hospital, Nei Monggol Autonomous Region.PARTICIPANTS: Random sampling was used toselect 6 hospitals from 10 hospitals affiliated to Tongliao City ofNei Monggot Autonomous Region. Totally 1 672 medical records of patients with ICH and 2 195 medical records of patients with CHD admitted to Department of Neurology and Department of Cardiovascular Intal Medicine of above-mentioned 6 hospitals between January 2003 and December 2005 were collected according to the investigation need.METHODS: The subjects, whose medical records were involved, were performed retrospective analysis with pre-prepared questionnaire Stroke and Coronary Heart Disease Epidemiologic Questionnaire. The main contents included: ①Social demography condition: The distributions of gender, age, nationality, etc. ②Previous history of disease: hypertension, diabetes mellitus, etc. ③Related risk factors: systolic blood pressure, diastolic blood pressure, total cholesterol, triglyceride, high-density lipoprotein cholesterol,low-density lipoprotein cholesterol, smoking, drinking and glucose (GLU). The database of Epidata was transformed to SPSS database. Single-and multiple-factor non-conditional Logistic regression analysis were performed on the data, and OR value and 95% CI were calculated. The distribution differences of risk factors for two diseases were compared.MAIN OUTCOME MEASURES: Single- and multi-factor non-conditional Logistic regression analysis results of each factor of patients.RESULTS: Single-factor non-conditional Logistic regression analysis showed that statistical significance existed in gender, age, nationality, smoking, drinking, history of hypertension, history of diabetes mellitus,hypertension, triglyceride (TG), and GLU ten factors (OR =0.199, OR 95% CI 0.142 - 0.280 to OR =7.484,OR 95% CI 6.186 - 9.054, P ＜ 0.01 ) . ②The results of multiple-factor non-conditional Logistic regression analysis showed 8 factors including age, gender, smoking, hypertension, history of hypertension, history of diabetes mellitus, GLU and TG (OR =0.203, OR 95% CI0.114 - 0.361 to OR =8.262, OR 95% CI 5.466 -12.491, P＜ 0.01) .CONCLUSION: ICH and CHD are the diseases induced by various risk factors. Significant difference exists in gender, age, smoking, hypertension, history of hypertension, GLU, history of diabetes mellitus and TG.