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目的探讨乙型肝炎患者肝移植术后乙型肝炎复发的预防方法。方法2001年6月~2006年5月对38例术前患有乙型肝炎的肝移植病人采用拉米夫定联合小剂量乙肝免疫球蛋白的预防方法。结果38例肝移植病人术后仅有1例乙型肝炎复发,所有病人总乙肝复发率为2.6%。结论拉米夫定联合小剂量乙肝免疫球蛋白对乙型肝炎患者肝移植术后乙型肝炎的复发起到很好的预防作用,值得临床推广应用。
Objective To investigate the prevention of hepatitis B recurrence in patients with hepatitis B after liver transplantation. Methods From June 2001 to May 2006, 38 patients with preoperative liver transplantation who had hepatitis B were treated with lamivudine combined with low-dose hepatitis B immunoglobulin. Results Of 38 patients with liver transplantation, only 1 had recurrent hepatitis B after operation, and the total recurrent hepatitis B was 2.6% in all patients. Conclusion Lamivudine combined with low-dose hepatitis B immunoglobulin can prevent hepatitis B recurrence after liver transplantation in patients with hepatitis B, which is worthy of clinical application.