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分子是一个整体,分子中的每一个原子或原子团总是相互影响、相互制约的。取代基对分子反应中心的影响除了通过熟知的电子效应和立体效应以外,还能发生直接的作用。即某些取代基可以部分地或完全地与反应中心成
A molecule is a whole. Every atom or group of atoms in a molecule always interacts with and restricts each other. The effect of substituents on the molecular reaction centers can have a direct effect, in addition to well-known electronic and stereoscopic effects. That is, certain substituents may be partially or completely reacted with the center of the reaction