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玻璃体手术结合对视网膜前膜的剖割已改善了复杂性视网膜脱离病例的预后。但是,神经胶质细胞、色素上皮细胞和成纤维细胞的增殖可继续在视网膜前后增生形成新的视网膜前膜。这些膜的收缩可使视网膜变形或再脱离,导致视网膜手术的失败。用抗炎药和抗代谢剂药物抑制细胞增殖,为改善增殖性玻璃体视网膜病变(PVR)的成功率提供了新的希望。一、PVR的病理、病因及发病率PVR发生于裂孔性视网膜脱离之后,为视
The vitrectomy combined with the pre-retinal membrane dissection has improved the prognosis of complex retinal detachment cases. However, proliferation of glial cells, pigment epithelial cells, and fibroblasts can continue to proliferate to form a new pre-retinal membrane around the retina. The contraction of these membranes can deform or re-detach the retina, resulting in the failure of retinal surgery. Inhibition of cell proliferation with anti-inflammatory and antimetabolite drugs offers new hope for improving the success rate of proliferative vitreoretinopathy (PVR). First, PVR pathology, etiology and incidence of PVR occurred after retinal detachment, as the visual