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目的探讨在上消化道出血中应用奥美拉唑治疗的临床效果。方法 90例上消化道出血患者,根据治疗方法不同分为研究组与对照组,各45例。对照组应用西咪替丁进行治疗,研究组应用奥美拉唑进行治疗,比较两组患者的止血效果、疗效及不良反应情况。结果研究组患者的止血时间、临床症状改善时间和住院时间均短于对照组,差异具有统计学意义(P<0.05)。研究组治疗总有效率为95.56%,明显高于对照组的82.22%,差异具有统计学意义(P<0.05)。研究组治疗过程中不良反应发生率为6.67%,明显低于对照组的22.22%,差异具有统计学意义(P<0.05)。结论在上消化道出血中应用奥美拉唑治疗,临床疗效确切,值得临床推广。
Objective To investigate the clinical effect of omeprazole in upper gastrointestinal bleeding. Methods 90 patients with upper gastrointestinal bleeding, according to different treatment methods were divided into study group and control group, 45 cases each. The control group was treated with cimetidine. The study group was treated with omeprazole. The hemostatic effects, curative effects and adverse reactions of the two groups were compared. Results The hemostasis time, clinical symptom improvement time and hospitalization time in the study group were shorter than those in the control group, with statistical significance (P <0.05). The total effective rate of the study group was 95.56%, which was significantly higher than that of the control group (82.22%), the difference was statistically significant (P <0.05). The incidence of adverse reactions in the study group was 6.67%, which was significantly lower than that of the control group (22.22%), the difference was statistically significant (P <0.05). Conclusion The application of omeprazole in upper gastrointestinal bleeding is clinically effective and worthy of clinical promotion.