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动脉导管未闭(PDA)手术的主要危险是出血,预防的方法是降压。现使用的硝普钠(SNP)存在引起反射性心动过速、耐药及潜在氰化物中毒的同题。为此,作者在60例PDA手术中进行降压观察,其中一部分加用不同剂量的普萘洛尔(心得安)或硬膜外阻滞。结果证明,普萘洛尔20μg/kg合用SNP和硬膜外阻滞合用SNP两种降压方法均能显著减少硝普钠用量。
The main risk of patent ductus arteriosus (PDA) surgery is bleeding, the method of prevention is antihypertensive. The sodium nitroprusside (SNP) currently in use has the same problem of causing reflex tachycardia, resistance and potential cyanide poisoning. To this end, the authors in 60 cases of PDA surgery for antihypertensive observation, some of them with different doses of propranolol (propranolol) or epidural block. The results show that propranolol 20μg / kg combined SNP and epidural block combined with SNP two kinds of antihypertensive method can significantly reduce the dosage of sodium nitroprusside.