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目的探讨胃肠间质瘤(GIST)的诊治方法。方法回顾安徽安庆市宜城医院2002年4月至2008年6月住院的胃肠间质瘤患者资料。结果肿瘤均位于胃肠道,均予以手术治疗。术后病理诊断5例为良性,8例为低度恶性和恶性,免疫组化CD34阳性9例,占69.2%,CD117阳性11例,占84.6%,复发2例,再切除1例。结论对于上腹部隐痛不适,消化道出血的中老年患者警惕胃肠间质瘤可能,CT对该病诊断帮助很大,GIST的诊断有赖于免疫组化,完整切除肿瘤是该病治疗的最佳手段。
Objective To investigate the diagnosis and treatment of gastrointestinal stromal tumors (GIST). Methods The data of patients with gastrointestinal stromal tumors admitted to Yicheng Hospital of Anqing City in Anhui Province from April 2002 to June 2008 were retrospectively reviewed. Results The tumors were located in the gastrointestinal tract, both were treated surgically. Pathological diagnosis of 5 cases were benign, 8 cases were low grade and malignant, immunohistochemical CD34 positive in 9 cases (69.2%), CD117 positive in 11 cases (84.6%), recurrence in 2 cases and resection in 1 case. Conclusion For upper abdominal pain and discomfort, gastrointestinal bleeding in elderly patients may be aware of gastrointestinal stromal tumors, CT diagnosis of the disease is very helpful, GIST diagnosis depends on immunohistochemistry, complete removal of the tumor is the best treatment of the disease means.