Conjugate Addition of Indoles to <i>α,β</i>-Unsaturated Ketones Using Bi

• 作 者: Tyler J. Rauwolf Zhijia Geng Z
• 机 构: LaboratoryforEnvironmentallyFriendlyOrganicSynthesis
• 出 处: 绿色与可持续化学(英文)
• 发表日期: 2019年3期
• 关键词: BISMUTH BISMUTH BROMIDE CONJUGATE Addition Green Chemistry INDOLES BismuthBismut

An efficient method for the conjugate addition of indoles to a variety of chalcones using BiBr3 in ethanol (190 proof) is reported. Products are isolated by a simple procedure that avoids an aqueous work up and extensive chromatography, thus minimizing wa