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目的观察宫颈鳞癌术中辅助髂内动脉灌注顺铂的治疗效果,探讨更有效的治疗方法。方法41例Ib~Ⅱ期患者分成治疗组(A组)21例和对照组(B)20例,两组均行宫颈癌根治术术后放射治疗,A组术中加双侧髂内动脉灌注顺铂,对两组进行观察。结果A组的5年内复发率或(和)转移率为9.52%,B组为45%,有显著差异性(P<0.05)。两组3年生存率均为100%,5年生存率A组为95.24%,B组为85%。结论术中辅助髂内动脉灌注顺铂可降低宫颈鳞癌治疗后5年内复发率和转移率,并可提高5年生存率。
Objective To observe the therapeutic effect of intra-arteria-aided internal iliac artery infusion of cisplatin in cervical squamous cell carcinoma and to explore more effective treatment. Methods Totally 41 patients with stage Ib ~ Ⅱ were divided into treatment group (group A) 21 and control group (group B) 20. Both groups underwent radiotherapy after radical mastectomy for cervical cancer. A group was treated with bilateral internal iliac artery perfusion Cisplatin, the two groups were observed. Results The recurrence rate or (metastasis) rate in group A within 5 years was 9.52%, while in group B 45%, there was significant difference (P <0.05). The 3-year survival rate was 100% in both groups, and the 5-year survival rate was 95.24% in group A and 85% in group B. Conclusions Intraoperative infusion of Cisplatin in the internal iliac artery can reduce the recurrence rate and metastasis rate within 5 years after cervical squamous cell carcinoma and improve the 5-year survival rate.