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患者:张××.男,26岁,民警。患慢性粒细胞性白血病(加速期)于1986.4.12入院,骨髓移植预处理:TBI700radCY+CCNU,经HLA配型后选其胞兄为供者行异基因骨髓移植(BMT)。植前患者与供者巨细胞病毒IgG抗体(CMV—IgG)滴度(ELISA)均为1:1600。移植后用MTX预防GVHD,+35天出现急性移植物抗宿主病(GVHD)Ⅱ°,用环胞素A、皮质激素等治疗二周后好转.自+46天出现咳嗽,咳少量粘痰,低热,并逐步加重而出
Patient: Zhang × ×. Male, 26 years old, police. Suffering from chronic myeloid leukemia (accelerated phase) was admitted to hospital in 1986.4.12, bone marrow transplantation pretreatment: TBI700radCY + CCNU, after HLA matching selected his brother for donor allogeneic bone marrow transplantation (BMT). Preimplantation and donor cytomegalovirus IgG antibody (CMV-IgG) titer (ELISA) were 1: 1600. After transplantation with MTX to prevent GVHD, 35 days after onset of acute graft-versus-host disease (GVHD) Ⅱ °, with cyclosporin A, corticosteroids and other treatment after two weeks of improvement.From +46 days cough, cough a small amount of phlegm, Low fever, and gradually increase out