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一氧化氮（nitricoxide，NO）广泛存在于脊椎动物各种细胞内，是一种新型的生物信息传递体，它的生物学意义成为近年来医学研究的热点。1987年Pain。erL‘］等揭示由血管内皮细胞释放的NO与内皮源性舒张因子（endotl。ellum－derivedrelaxingfactor，EDRF）同质，1988年Hibl）s
Nitric oxide (NO) is widely present in various cells of vertebrates and is a new type of biological information transmitter. Its biological significance has become a hot topic in medical research in recent years. Pain, 1987. erL’] et al. revealed that NO released from vascular endothelial cells is homogenous to endotl-ellreleasing factor (EDRF), 1988 Hibl)s