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目的探讨糖尿病肾脏疾病(DKD)的治疗方法。方法将我院糖尿病专科2003年1月至2008年10月DKD50例资料,于治疗前后进行对比。治疗前1 d及治疗6个月结束后1 d均测血压、空腹血糖(FPG)、糖化血红蛋白(HbA1 c)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿蛋白、UAER、ALB/Cr进行对比分析。结果治疗后尿蛋白、血压、糖化血红蛋白、ALB/Cr有明显改善。结论严格控制血糖,选用血管紧张素转换酶抑制剂(ACEI)/血管紧张素Ⅱ受体拮抗剂(ARB)加利尿剂控制血压等综合治疗,能减少尿蛋白的排泄,有效延缓DKD的病情进展。
Objective To investigate the treatment of diabetic kidney disease (DKD). Methods The data of DKD 50 cases in our hospital from January 2003 to October 2008 were compared before and after treatment. Blood pressure, fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), total cholesterol (TC), triglyceride (TG) and high density lipoprotein cholesterol (HDL) were measured on the first day before treatment and at the end of the 6th month after treatment. -C), low density lipoprotein cholesterol (LDL-C), urinary protein, UAER, ALB / Cr were compared. Results After treatment, urinary protein, blood pressure, glycosylated hemoglobin, ALB / Cr were significantly improved. Conclusion Strict glycemic control and ACE-inhibitor / angiotensin II receptor antagonist (ARB) combined with diuretic control of blood pressure and other comprehensive treatment can reduce urinary protein excretion and delay the progress of DKD .