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目的观察生物羊膜移植联合丝裂霉素C(MMC)在小梁切除术中应用的临床疗效。方法对46例(59眼)青光眼患者小梁切除术中应用羊膜移植和MMC的治疗进行回顾性分析,术后随访1年,观察术后的视力、眼压、滤过泡和并发症情况。结果随访观察1年,视力改善11眼(18.6%),视力降低6眼(10.2%),视力不变42眼(71.7%),眼压控制正常51眼(86.4%),功能性滤过泡22眼(77.9%)。结论青光眼小梁切除术中联合应用生物羊膜和MMC可以减少疤痕的形成,提高滤过功能,降低眼压,提高手术成功率。
Objective To observe the clinical effect of biological amniotic membrane transplantation combined with mitomycin C (MMC) in trabeculectomy. Methods 46 patients (59 eyes) with traumatic glaucoma were treated by amniotic membrane transplantation and MMC with trabeculectomy. The patients were followed up for 1 year. Visual acuity, intraocular pressure, filtration bleb and complication were observed. Results One year follow-up showed that visual acuity was improved in 11 eyes (18.6%), visual acuity was decreased in 6 eyes (10.2%), visual acuity was unchanged in 42 eyes (71.7%), intraocular pressure was normal in 51 eyes (86.4% 22 eyes (77.9%). Conclusion Glaucoma trabeculectomy combined with biological amniotic membrane and MMC can reduce the formation of scars, improve filtration function, reduce intraocular pressure and improve the success rate of surgery.