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目的:探讨后腹腔镜肾上腺全部切除与部分切除治疗醛固酮瘤的疗效。方法:收集我院收治的醛固酮瘤患者60例,随机分为部分切除组和全切除组,每组30例,分别给予肾上腺部分切除以及肾上腺全切除手术,手术结束后,对所有患者的住院时间、术中出血量、手术时间、血清钾、血清醛固酮水平以及患者的治疗效果进行检测并比较。结果:手术后,部分切除组和全切除组患者血清钾水平均升高(P<0.05),醛固酮水平均降低(P<0.05);与全切除组相比,部分切除组患者的术中出血量以及住院时间较短(P<0.05),血清钾水平较高(P<0.05),血清醛固酮水平较低(P<0.05);两组患者的手术时间以及临床疗效无明显差异(P>0.05)。结论:后腹腔镜肾上腺部分切除术较全切除术能够缩短醛固酮瘤患者住院时间,减少手术出血量,升高血清钾水平,降低醛固酮水平。但两种术式的手术时间以及临床疗效相当,对临床有指导意义。
Objective: To investigate the effect of total laparoscopic adrenalectomy and partial resection of aldosterone. Methods: Sixty patients with aldosteronoma admitted to our hospital were randomly divided into partial resection group and total resection group, with 30 cases in each group. Partial adrenalectomy and total adrenalectomy were performed. At the end of the operation, all the patients were hospitalized , Intraoperative blood loss, operation time, serum potassium, serum aldosterone levels and the therapeutic effect of the patients were tested and compared. Results: After surgery, the levels of serum potassium in partial resection group and total resection group were significantly increased (P <0.05) and aldosterone levels were decreased (P <0.05). Compared with the resection group, the intraoperative bleeding in partial resection group (P <0.05), serum potassium level was higher (P <0.05) and serum aldosterone level was lower (P <0.05). There was no significant difference in operative time and clinical efficacy between the two groups (P> 0.05) ). Conclusions: Retroperitoneal laparoscopic radical resection of adrenalectomy can shorten the hospitalization time of patients with aldosteronoma, reduce the amount of bleeding, increase the level of serum potassium and decrease the level of aldosterone. However, the two surgical procedures and the clinical efficacy of considerable clinical significance.