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目的探讨益气活血中药联合西药贝那普利对冠状动脉粥样硬化性心脏病(CHD)患者心功能相关指标的影响。方法选取2015年1月至2016年6月广州市南沙区中医医院心血管内科门诊及住院部收治的120例CHD患者作为研究对象,均采用益气活血中药联合贝那普利进行治疗,比较患者治疗前后心功能分级、心电图缺血性ST段改善情况及血流动力学指标。结果治疗后心功能分级为Ⅰ级、Ⅱ级患者比例明显高于治疗前,差异均有统计学意义(均P<0.05);本组患者经治疗后,有97例患者缺血性ST段得到改善,改善率为80.8%;患者治疗后心肌收缩力(MCF)、左心室射血分数(LVEF)、左心室舒张末期容量(EDV)、心肌耗氧量(MVO)与治疗前比较,差异均有统计学意义(均P<0.05)。结论益气活血中药联合西药贝那普利对CHD患者心功能相关指标改善具有积极意义,有利于疾病康复。
Objective To investigate the effects of Yiqi Huoxue Medicine combined with western medicine benazepril on cardiac function related indexes in patients with coronary atherosclerotic heart disease (CHD). Methods From January 2015 to June 2016, 120 patients with CHD admitted to the Department of Cardiology, Nansha District Hospital of Traditional Chinese Medicine, Guangzhou were enrolled in this study. All the patients were treated with Yiqi Huoxue Chinese medicine combined with benazepril. Heart function before and after treatment, ischemic ST segment ECG improvement and hemodynamic parameters. Results After treatment, the scores of grade Ⅰ and grade Ⅱ were significantly higher than those before treatment (all P <0.05). After the treatment, 97 cases of ischemic ST were obtained The improvement rate was 80.8%. The differences of myocardial contractility (MCF), left ventricular ejection fraction (LVEF), left ventricular end-diastolic volume (EDV) and myocardial oxygen consumption (MVO) There was statistical significance (all P <0.05). Conclusions Yiqi Huoxue combined with western medicine benazepril has a positive effect on the improvement of cardiac function-related index in patients with CHD, which is benefit to the rehabilitation of the disease.