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应用彩色多普勒检测20例正常新生儿和20例缺氧缺血性脑病（HIE）患儿肾动脉血流变化。结果正常新生儿第1天肾动脉收缩期峰值流速高于日龄第2、3、5天，但无统计学显著意义。窒息组日龄第1天肾动脉Vmax、Vmin、TAMX均有不同程度降低，Vmin日龄第1、3天与正常组对照有显著和极显著性意义。不同检查日龄窒息组RI均较正常组升高，且有统计学显著意义。研究提示窒息时以Vmin降低和RI升高为特点，导致肾灌注量减少。RI＞0．8作为新生儿肾动脉阻力指数增高的标准。中、重度HIE患儿均表现尿少、Vmin降低、RI升高。1例重度HIE患儿Vmin为零，RI＞1，一日尿量仅40ml，是肾血管痉挛、严重缺血的标志。提示检测HIE患儿肾血流变化是辅助临床诊断肾功能受损的手段。
Color Doppler echocardiography was used to detect renal artery blood flow in 20 normal neonates and 20 hypoxic-ischemic encephalopathy (HIE) children. Results The peak systolic velocity of renal artery in normal newborns was higher than that of day 2, 3 and 5 on the first day of neonate, but there was no statistical significance. On the first day of asphyxia group, Vmax, Vmin and TAMX in renal arteries all decreased to different extents. There was significant and extremely significant difference between the first and third day of Vmin day and the control group. RI in different groups of asphyxial day were higher than the normal group, and there was statistically significant. Studies suggest that asphyxia is characterized by a decrease in Vmin and RI, resulting in a decrease in renal perfusion. RI> 0.8 as a measure of renal artery resistance index increase in newborns. Moderate and severe HIE children showed less urine, Vmin decreased, RI increased. One case of severe HIE children with Vmin zero, RI> 1 day urine output of only 40ml, is a sign of renal vasospasm, severe ischemia. Prompt detection of renal blood flow changes in children with HIE is a means of clinical diagnosis of impaired renal function.