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目的:比较瑞芬太尼复合丙泊酚静脉全麻用于小儿眼科手术麻醉的安全性、有效性及可控性。方法:选择期眼科手术的患儿40例,随机分为两组:瑞芬太尼复合丙泊酚静脉全麻组(观察组)和异氟吸人全麻组(对照组),每组20例。观察组麻醉维持采用静脉持续输注瑞芬太尼0.1ug(kg min)和丙泊酚,对照组麻醉组维持用氟醚吸入,术中根据麻醉深度调整异氟醚吸人浓度和丙泊酚输注速度,观乏、气管拔管和清醒捍间,苏醒后躁动和恶心呕吐的发生率。察组麻醉苏醒时间、自主呼吸恢复时间、意识恢复时间和拔管时间均明显短于对照组(p<0.05)。观察组术后躁动、恶心呕吐发生率,均低于对组(p<0.05)。结论:瑞芬太复合泊酚静脉全麻可为小儿眼科手术提供稳定血流动力学状态,快速苏醒,适用于小儿眼科手术麻醉。
Objective: To compare the safety, efficacy and controllability of remifentanil and propofol intravenous anesthesia for pediatric ophthalmic anesthesia. Methods: Forty children with selective ophthalmic operation were randomly divided into two groups: remifentanil combined with propofol intravenous anesthesia (observation group) and isoflurane inhalation anesthesia group (control group), with 20 example. In the observation group, remifentanil 0.1μg (kg min) and propofol were continuously administered by intravenous infusion while those in the control group were maintained with fluoroether inhalation. Intravenous anesthesia was used to adjust isoflurane inhalation concentration and propofol Infusion speed, lack of observation, tracheal extubation and sober defend, after the onset of restlessness and nausea and vomiting. The anesthesia recovery time, spontaneous breathing recovery time, recovery time and extubation time were significantly shorter than the control group (p <0.05). The incidence of postoperative agitation and nausea and vomiting in the observation group were lower than those in the control group (p <0.05). Conclusion: Refentanil combined with intravenous epinephrine anesthesia can provide steady hemodynamic status in pediatric ophthalmic surgery and wake up rapidly. It is suitable for pediatric ophthalmic anesthesia.