论文部分内容阅读
1.HCV 研究的历史目前肝炎研究的最大的课题是 HCV 的发现。在输血后肝炎中,除乙型外,NANB 型约占全部受血者的10～20%,全日本的年发病人数达20万之多。此前不久,HNANB 肝炎还仅能通过排除法来诊断。此间,美国 CDC(疾病监测中心)及 NIH(国家卫生研究院)实验室等进行的黑猩猩病毒感染模型获得成功,HNANBV 的许多特性也得到明确,主要包括:①连续感染几代的感染血清,经过一定潜伏期,可使黑猩猩发生有肝功改
1. The history of HCV research Currently the biggest issue of hepatitis research is the discovery of HCV. In the post-transfusion hepatitis, in addition to type B, NANB type accounted for about 10 to 20% of all recipients, the annual number of patients in Japan reached as many as 200,000. Not long ago, HNANB hepatitis was diagnosed only by exclusion. Here, the success of the chimpanzee virus infection model conducted by the CDC (Disease Surveillance Center) and NIH (National Institutes of Health) laboratories in the United States has also clarified many of the features of HNANBV, including the following: ① Infected sera from several generations of infection, A certain incubation period, can make chimpanzees have liver function