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随着世界和我国药物制剂理论的发展和现代工业化制剂技术的不断改进,促进了对药物的剂型因素,机体的生物因素,工艺性加工技术及药效之间的相互研究与发展。乳剂作为药物剂型的一种形式,包括软膏剂和乳液剂,因机体吸收较好,生物利用度高,现代加工技术成熟,并伴随着缓释、控释技术的研究与应用而日益受到医药界的瞩目。本文通过工作实践,浅析药物乳剂的乳化原理及其乳化技术。 一、乳化原理 乳剂(Emulsions),在医药行业中,按物理化学的特性及用药途径,可分为软膏(Ointmonts)剂,主要是外用药;乳液剂(Emulsions)有:口服乳剂、静脉乳剂、部分外用乳液、擦剂等。乳剂是两种互不相溶的液相组成的非均相分散体系,也即是一种或几种液体以液
With the development of the world and the theory of pharmaceutical preparations in our country and the continuous improvement of the modern industrialized preparation technology, we have promoted the mutual research and development of the drug formulation factors, the biological factors of the body, the process technology and the efficacy. Emulsion as a form of drug formulation, including ointment and emulsion, due to the body better absorption, high bioavailability, modern processing technology is mature, along with sustained-release, controlled-release technology research and application and increasingly by the pharmaceutical industry The attention. This article through the practice of practice, analysis of emulsion emulsification principle and emulsification technology. First, the principle of emulsification Emulsions, in the pharmaceutical industry, according to the physical and chemical characteristics and route of administration can be divided into ointment (Ointmonts) agents, mainly external use; Emulsions are: oral emulsion, intravenous emulsion, Partially applied lotion, liniment and so on. Emulsions are two heterogeneous dispersion of liquid phase composition, which is one or more liquid to liquid