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本文报告了30例鼠疫患者的间接血凝反应及3例腺鼠疫患者的血凝抗体动态,探讨了间接血凝试验对鼠疫患者诊断的价值。 30例患者于病后5～10天均可出现血凝抗体(1:80～1:81920),其血凝滴度比EV活菌苗接种者为高。一些病例的血凝抗体可维持4～6年。但细菌学检查仅2例为鼠疫菌阳性。可以认为间接血凝试验比细菌学检查更为敏感,它可用于鼠疫患者的诊断。若患者曾有预防接种史或血凝滴度较低时,可采用双份(急性和恢复期)血凝试验,其滴度升高4倍以上亦可作出诊断。
This article reports the hemagglutination of 30 cases of plague patients and 3 cases of bubonic antibodies in patients with bubonic plague, and discusses the indirect hemagglutination test for the value of the diagnosis of plague patients. Thirty patients had hemagglutination antibody (1:80 to 1: 81920) in 5 to 10 days after the illness, and their hemagglutination titer was higher than that of EV live vaccine inoculation. In some cases, hemagglutination antibodies can be maintained for 4 to 6 years. However, only 2 of the bacteriological tests were positive for Y. pestis. Indirect hemagglutination test can be considered more sensitive than bacteriological examination, it can be used for the diagnosis of plague patients. In patients with a history of vaccination or low titer of blood clotting, duplicate (acute and convalescent) hemagglutination tests with a 4-fold or greater titer may also be used for diagnosis.