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目的:寻找一种有效的治疗脑血管痉挛的新方法。方法:蛛网膜下腔出血(SAH)后所致的症状性脑血管痉挛(CVS)病人16例,采用等容稀释加多巴酚丁胺和胞二磷胆碱进行治疗。结果:治疗后脑电和CT检查正常。基底动脉TCD血流速度和心输出量分别由治疗前的51±13.6cm/s和4.60±1.6L/min增加到治疗后的70±12.6cm/s和11.5±2.86L/min(P<0.05)。除两例肢体肌力由原来的Ⅲ级恢复到Ⅳ级外,其余均恢复正常。总有效率高达94%。结论:该法治疗CVS有效。
Objective: To find a new method for the treatment of cerebral vasospasm. METHODS: Sixteen patients with symptomatic cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) were treated with isodose dilution plus dobutamine and citicoline. Results: After treatment, EEG and CT examination were normal. Basilar artery TCD blood flow velocity and cardiac output increased from 51 ± 13.6 cm / s and 4.60 ± 1.6 L / min before treatment to 70 ± 12.6 cm / s and 11.5 ± 2 after treatment, respectively .86 L / min (P <0.05). In addition to the two cases of limb muscle strength restored from the original level Ⅲ to Ⅳ, the rest were normal. The total efficiency up to 94%. Conclusion: This method is effective in treating CVS.