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奥曲肽是人工合成的生长抑素类似物,具有抑制胰腺外分泌的作用,因而有人主张用于急性胰腺炎的特异性治疗。现研究奥曲肽在急性胰腺炎中的疗效。 方法:在32家医院中,符合中到重度急性胰腺炎的诊断标准、起病在96小时内的患者被随机分到以下3组;P组接受安慰剂治疗,O1和O2组分别接受每日3次100μL/和200μg奥曲肽皮下注射治疗,疗程7天。严格用随机分组和双盲程序,而且对各组患者均给予急性胰腺
Octreotide is a synthetic somatostatin analogue, with the role of inhibition of pancreatic exocrine, which was advocated for the specific treatment of acute pancreatitis. Now study the efficacy of octreotide in acute pancreatitis. Methods: In 32 hospitals, the diagnostic criteria of moderate-to-severe acute pancreatitis were met. Patients with onset within 96 hours were randomly assigned to the following three groups: P group received placebo, O1 and O2 groups received daily 3 times 100μL / and 200μg octreotide subcutaneous injection therapy, treatment for 7 days. Strict use of randomized and double-blind program, but also for each group of patients were given acute pancreas