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在病理状况及不同生理条件刺激时，左右心功能和结构改变的不一致已被广泛发现，但是对于造成左右心不一致变化的原因尚缺乏认识。本研究利用双向电泳方法分析和比较了应激蛋白在常氧及低氧灌流的离体大鼠左右心肌的诱导。结果表明，三个分子量为７０ｋＤａ（Ｓｐ６８，７０和７２）ｐＩ６．３－７．３的应激蛋白在左右心肌中均显著增加，并且应激蛋白在右心的合成量要高于左心。这说明右心对缺血灌流刺激的应答不同于左心，应激蛋白对左右心的保护程度不一样。此外，左右心的过氧化氢酶活力均显著下降，提示对离体灌流的大鼠心脏，氧化应激可能是诱导应激蛋白合成的一个重要原因，并且左右心应激蛋白增加不一致的原因很可能与左右心自身的结构及所处的状况有关。
In the pathological conditions and different physiological conditions to stimulate, left and right cardiac function and structural changes in the inconsistency has been widely found, but for the left and right heart caused by the reasons for the change is still lack of understanding. In this study, the two-dimensional electrophoresis method was used to analyze and compare the induction of stress proteins in left and right myocardium of isolated rat in normoxia and hypoxia perfusion. The results showed that the three stress proteins with a molecular weight of 70 kDa (Sp68, 70 and 72) pI6.3-7.3 were significantly increased in the left and right myocardium, and the synthesis of the stress protein in the right heart was higher than that of the left heart. This shows that right heart on ischemic perfusion stimulation response is different from the left heart, stress protein left and right heart protection is not the same. In addition, both left and right cardiac catalase activity were significantly decreased, suggesting that perfused rat heart, oxidative stress may be induced by stress protein synthesis is an important reason, and left and right cardiac stress protein increase is inconsistent reason It may be related to the structure of the left and right heart and the situation in which it is located.