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用含11％花生油、茶油、牛油的饲料分别饲养SD大鼠，观察其血清和心、肝、脑丙二醛（MDA）、血清和肝超氧化物歧化酶（SOD）水平、生物膜磷脂脂肪酸组成及膜流动性的改变。结果发现：花生油组心线粒体及牛油组RBC膜磷脂脂肪酸含量与摄入脂肪酸呈正相关（r分别为0.6275和0.6967，P＜0.01）。喂饲花生油引起生物膜磷脂多不饱和脂肪酸含量增加，膜流动性增高，血清和肝SOD水平较低（分别为3.76±1.61mg／L、616±163μg／g），血清MDA较高（8.70±1.71μmol／L），提示脂质过氧化程度较高。喂饲茶油引起膜磷脂单不饱和脂肪酸含量增加，膜流动性和血清SOD（5.66±2.00mg／L）较高，血清及脑MDA较低（5.92±1.15μmol／L，2.45±0.44μmol／g），提示脂质过氧化程度较低。喂饲牛油引起膜磷脂饱和脂肪酸含量增加，膜流动性较低，血清及肝SOD较高（5.79±0.56mg／L，886±99μg／g），血清MDA较低（7.04±1.66μmol／L），脑MDA较高（3.96±1.68μmol／g），脂质过氧化程度介于花生油组与茶油组之间。
SD rats were fed with 11% peanut oil, tea oil and butter oil respectively, and their serum, heart, liver and brain malondialdehyde (MDA), serum and liver superoxide dismutase (SOD) Changes in phospholipid fatty acid composition and membrane fluidity. The results showed that RBC phospholipid fatty acid content in peanut oil group was positively correlated with fatty acid intake (r = 0.6275 and 0.6967, respectively, P <0.01). Peanut oil feeding biofilm causes increased phospholipid polyunsaturated fatty acid content, increased membrane fluidity is low, and serum levels of liver SOD (respectively 3.76 ± 1.61mg / L, 616 ± 163μg / g), higher serum MDA (8.70 ± 1.71μmol / L), suggesting a higher degree of lipid peroxidation. Feeding tea membrane phospholipids caused an increase in monounsaturated fatty acids, membrane fluidity and serum SOD (5.66 ± 2.00mg / L) higher, lower serum and brain MDA (5.92 ± 1.15μmol / L, 2.45 ± 0.44μmol / g), suggesting a lower degree of lipid peroxidation. Tallow cause feeding of saturated fatty acids of membrane phospholipids to increase membrane fluidity is low, higher serum and liver SOD (5.79 ± 0.56mg / L, 886 ± 99μg / g), low serum MDA (7.04 ± 1.66μmol / L ), Brain MDA was higher (3.96 ± 1.68μmol / g), the degree of lipid peroxidation was between peanut oil group and tea oil group.