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为探索乙型肝炎疫苗免疫后的加强接种的时间和剂量．对44例未达到乙肝抗体保护水平的儿童，进行加强免疫的研究。结果表明二种剂量均能取得令人满意的抗体水平。剂型Ⅰ抗-HBSGMT457．09mIu／ml，剂型Ⅱ398．11mIu／ml，剂型Ⅲ489．78mIu／ml。推荐双阳母亲的儿童加强接0、1月接种剂量10ug～10ug疫苗。阴性母亲的儿童加强接0、1接种剂量5ug～5ug疫苗。通过加强免疫从而有效的阻断乙肝病毒母婴间传播和水平传播。
To explore the time and dose of intensive vaccination after hepatitis B vaccine immunization. Forty-four children who did not reach the level of hepatitis B antibody protection were studied for booster immunization. The results showed that both doses yielded satisfactory antibody levels. Formulation I anti-HBSGMT 457.09 mIu / ml, Formulation II 398.11 mIu / ml, Formulation III 489.78 mIu / ml. Recommended Shuangyang mothers to strengthen the child 0, January vaccination dose 10ug ~ 10ug vaccine. Negative mothers of children to strengthen the 0,1 vaccination dose 5ug ~ 5ug vaccine. By strengthening the immune and thus effectively blocking the transmission of hepatitis B virus between mother and infants and horizontal transmission.