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目的 :通过社区鼻咽癌EB病毒血清学普查发现EB病毒抗体阳性人群 ,从抗体阳性者中发现早期鼻咽癌患者。方法 :社区血清学普查检出EB病毒抗体 (VCA IgA)阳性者 ,并应用间接鼻咽镜检查鼻咽部 11977人 ,发现异常即取组织送病理检查。结果 :病理确诊 174例 ,早期 15 1例 ,早诊率 86 78% ,鼻咽原发灶位于顶后壁 95例占 5 4 60 % ,侧壁 60例占 34 4 % ,前壁 1例占 0 5 7%最少 ;68例原发灶直径 <0 5cm占 39 0 8%。结论 :鼻咽癌血清学普查作为初筛的手段 ,可以得出鼻咽癌的高危人群。间接鼻咽镜的应用 ,可以检出鼻咽癌临床早期患者 ,适用于社区 ,特别是农村和边远地区大人群普查
OBJECTIVE: To detect Epstein-Barr virus (EBV) positive patients by community serological survey of Epstein-Barr virus in nasopharyngeal carcinoma and to identify early NPC patients from antibody positive individuals. Methods: Community serological screening detected positive for Epstein-Barr virus (VCA IgA), and indirect nasopharyngeal examination of nasopharyngeal 11977 people were found to be abnormal tissue sent for pathological examination. Results: The pathological diagnosis of 174 cases, early 15 1 cases, early diagnosis rate of 86 78%, 95 cases of nasopharyngeal apical wall in 95 cases accounted for 5460%, 60 cases accounted for 34 4%, anterior wall in 1 case 0 5 7% at least; 68 cases of primary tumor diameter <0 5cm 39 0 8%. Conclusion: Serological survey of nasopharyngeal carcinoma as a preliminary screening method can be drawn high-risk population of nasopharyngeal carcinoma. Indirect nasopharyngeal mirror application can detect early clinical patients with nasopharyngeal carcinoma, suitable for community, especially in rural areas and remote areas large population census