论文部分内容阅读
目的:总结射频消融(RFA)在不可切除结直肠癌肝转移(CLM)中的应用,并对治疗现状和发展前景进行分析。方法:检索PubMed及CHKD期刊全文数据库,以“结直肠癌、肝转移、射频消融、分析”为关键词,检索2001-01-2010-03有关“RFA对不可切除CLM中的应用及其价值”方面的文献,纳入分析26篇。结果:RFA单独或联合应用可提高不可切除CLM的疗效,尤其对于直径≤3 cm转移灶的疗效已经得到肯定。结论:RFA提高了不可切除CLM的总体疗效,但仍需要随机大样本循证医学证据,其疗效依赖于RFA技术水平的提高及医生经验的不断积累。
Objective: To summarize the application of radiofrequency ablation (RFA) in unresectable colorectal cancer liver metastasis (CLM), and to analyze the status of treatment and development prospects. Methods: The full-text database of PubMed and CHKD journals was searched and the key words of “colorectal cancer, liver metastasis, radiofrequency ablation, analysis” were searched. The application of RFA in unresectable CLM Its value "literature, included in the analysis of 26 articles. Results: RFA alone or in combination could improve the efficacy of unresectable CLM, especially for the metastases ≤3 cm in diameter. CONCLUSIONS: RFA improves the overall efficacy of unresectable CLM, but evidence-based medical evidence of randomized large samples is still needed, and its efficacy relies on improvements in RFA technology and the accumulation of physician experience.