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肾素－血管紧张素系统（ＲＡＳ）在心血管、肾脏和内分泌功能调节中起着关键性的作用，这些生物性活动主要通过血管紧张素Ⅱ（ＡＴⅡ）和特异的膜受体作用来调控的。随着分子生物学技术的发展和应用，人们发现在许多组织或器官如心脏中具有其各自的局部ＲＡＳ。ＡＴⅡ通过旁分
The renin-angiotensin system (RAS) plays a key role in the regulation of cardiovascular, renal and endocrine functions. These biological activities are mainly regulated by the action of angiotensin II (AT II) and specific membrane receptors. With the development and application of molecular biology techniques, one has found that it has its own local RAS in many tissues or organs, such as the heart. AT Ⅱ by the side