论文部分内容阅读
小儿中枢神经系统曲菌感染临床少见,误诊率高。笔者特将误诊的4例分析如下,以供参考。临床资料:4例中男3例,女1例。年龄8月～9岁。前3例均有原发病,溺水后肺炎、支气管肺炎,迁延性腹泻各1例。治疗中均给予大剂量广谱抗生素、激素等治疗。治疗1个月后感染征象仍未控制,体温波动不稳,血象持续增高,最后出现抽搐、昏迷、脑膜刺激征及各种病理反射。后1例以低热、咳嗽1月余,头痛半月、抽搐嗜睡2天入院,按结核性脑膜炎经正规抗痨治疗,病情非但不好转且进行性加重,最后消耗衰竭死亡。本组4例均死亡,其中3例经尸解证实为全身播散性曲菌病并中枢神经系统感染。1例经脑脊液培养证实。
Pediatric CNS germ infection is rare and the rate of misdiagnosis is high. I will misdiagnosed 4 cases as follows, for reference. Clinical data: 4 cases of 3 males and 1 females. Age from August to 9 years old. The first three cases were primary disease, pneumonia after drowning, bronchial pneumonia, persistent diarrhea in 1 case. Treatment are given large doses of broad-spectrum antibiotics, hormones and other treatment. After 1 month of treatment, the signs of infection were still not controlled. The body temperature fluctuated unsteadily and blood continued to increase. Finally, convulsions, coma, meningeal irritation and various pathological reflexes were observed. After 1 case of low fever, cough for more than a month, headache and a half months, convulsions and drowsiness 2 days admission, according to tuberculous meningitis by anti-tuberculosis treatment, the condition is not only not improve and progressively worse, and eventually exhaustion death. The group of 4 patients were killed, of which 3 cases of autopsy confirmed systemic disseminated aspergillosis and central nervous system infections. One case was confirmed by cerebrospinal fluid culture.