Copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles from imidoyl chlorides

• 出 处: Chinese Chemical Letters
• 发表日期: 2012年05期
• 关键词: catalyzed moderate equiv antibacterial benzene Proline substituted distillation

A strategy for the synthesis of 1,2-disubstituted benzimidazoles has been developed and a variety of 1,2-disubstituted benzimidazoles were obtained from imidoyl chlorides and o-haloanilines via copper(I)-catalyzed reaction in moderate yields.

A strategy for the synthesis of 1,2-disubstituted benzimidazoles has been developed and a variety of 1,2-disubstituted benzimidazoles were obtained from imidoyl chlorides and o-haloanilines via copper (I) -catalyzed reaction in moderate yields.