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自发高血压大鼠(SHR)虽被广泛应用于医学科研中,但对其心脏功能的增龄性变化尚缺乏了解。本实验选用雄性SHR与正常对照WKY鼠,各分为五个年龄组:1组(4～6周)、2组、3组、4组、6组(16～18周)。乙醚麻醉下行右颈总动脉及左心室插管测取各有关心功能指标。静脉注射氯化钾致心跳停止后,于左心
Although spontaneously hypertensive rats (SHR) are widely used in medical research, their understanding of the age-related changes of cardiac function is still poorly understood. In this study, male SHR and normal control WKY mice were selected and divided into five age groups: group 1 (4-6 weeks), group 2, group 3, group 4 and group 6 (16-18 weeks). Ether anesthesia under the right common carotid artery and left ventricular intubation to measure the relevant cardiac function. After intravenous injection of potassium chloride caused cardiac arrest, in the left heart