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目的观察黄芪注射液佐治小儿原发性肾病综合征的效果。方法将57例原发性肾病综合征患儿随机分为对照组和观察组,两组均采用泼尼松中程疗法,观察组在此基础上加用黄芪注射液。观察两组治疗前后24h尿蛋白定量,血浆白蛋白、总蛋白、总胆固醇、甘油三酯的变化。结果 2组治疗后均见尿蛋白减少,血浆白蛋白、总蛋白升高,总胆固醇和甘油三酯下降,与治疗前比较差异有统计学意义(P<0.01);观察组与对照组治疗后比较,对照组尿蛋白减少,血浆白蛋白、总蛋白升高,总胆固醇和甘油三酯下降更明显,差异有统计学意义(P<0.01)。结论加用黄芪注射液佐治小儿原发性肾病综合征效果良好。
Objective To observe the effect of astragalus injection on children with primary nephrotic syndrome. Methods Fifty-seven children with primary nephrotic syndrome were randomly divided into control group and observation group. Both groups received prednisone mid-course therapy. Astragalus injection was used in the observation group. Urinary protein excretion, plasma albumin, total protein, total cholesterol and triglyceride were observed before and after treatment in two groups. Results After treatment, both urinary protein decreased, serum albumin, total protein increased, total cholesterol and triglyceride decreased, with statistical significance (P <0.01); the observation group and the control group after treatment Compared with the control group, urinary protein decreased, plasma albumin, total protein increased, total cholesterol and triglyceride decreased more significantly, the difference was statistically significant (P <0.01). Conclusion plus Astragalus injection in children with primary nephrotic syndrome effect is good.