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我们于1996年12月24日为1例严重肺功能损害患者施行右侧同种异体肺移植。术后患者存活了45天,死于脑干、脑实质多发性出血。在此期间,成功地控制了4次急性排斥反应及防止了严重肺部感染的进一步蔓延。认为(1)诱导-辅助性T细胞/抑制性T细胞(TH/TS)的监测有助于早期发现肺急性排斥反应;(2)支气管纤维镜检查对防治术后并发症有重要作用;(3)术后应选用有针对性抗生素及联合应用抗真菌药物抗感染
On December 24, 1996, we performed a right allograft lung transplant in 1 patient with severe pulmonary impairment. After the patient survived for 45 days, died of brain stem, brain parenchymal hemorrhage. During this period, four acute rejection events were successfully controlled and further spread of severe pulmonary infection prevented. It is believed that (1) induction of T helper / suppressor T cells (TH / TS) can be helpful in early detection of acute lung rejection; (2) bronchofiberscopy plays an important role in the prevention and treatment of postoperative complications; 3) after surgery should be targeted antibiotics and anti-fungal drugs combined anti-infective