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目的:应用超声应变率成像技术(strain rate imaging,SRI)测定糖耐量异常患者腹主动脉前、后壁的位移(TT)、应变(ST)及应变率(SR)等参数,观察糖耐量异常患者腹主动脉弹性的变化情况,为早期预防、诊疗糖耐量异常患者腹主动脉疾病提供依据。方法:选择自2011年7月至2013年12月我院门诊及住院的糖耐量异常患者20例,所选患者符合糖耐量异常诊断标准,另选30例体检正常者做为对照组。应用SRI技术获取同步的位移(TT)曲线,应变(ST)曲线和应变率(SR)曲线,获得每处的最大位移(TT)、最大应变峰值(ST)、收缩期、舒张早期和舒张晚期的应变率峰值(SRs、SRe、SRa)。结果:腹主动脉前后壁组织多普勒指标比较,对照组前、后壁组织多普勒各指标差异均具有统计学意义(P<0.05),糖耐量异常组的前、后壁组织多普勒指标SRs、SRe、SRa指标均具有统计学差异(P<0.05),前壁以SRs指标改变最为明显。糖耐量异常组前壁及后壁ST值分别与对照组比较,均有所下降。差异均有统计学意义(P<0.05);糖耐量异常组指标(SRs、SRe、SRa)绝对值比对照组减低,差异均有统计学意义(P<0.05)(见表4、5),应变率指标以SRs改变更明显。结论:超声应变率成像可作为评价糖耐量异常患者腹主动脉弹性的方法,为临床提供有价值的治疗和预后信息。
OBJECTIVE: To determine the TT, ST and SR parameters of anterior and posterior abdominal aorta in patients with impaired glucose tolerance by using strain rate imaging (SRI) The change of elasticity of abdominal aorta in patients provides basis for early prevention and treatment of abdominal aorta disease in patients with impaired glucose tolerance. Methods: From July 2011 to December 2013, 20 outpatients and inpatients with impaired glucose tolerance in our hospital were selected. The patients were selected according to the diagnostic criteria of impaired glucose tolerance and the other 30 normal subjects were selected as the control group. The TT, ST, systolic, early diastolic and late diastolic phase were obtained by using the SRI technique to obtain the synchronous TT, ST and SR curves. Of the peak strain rate (SRs, SRe, SRa). Results: Compared with the Doppler index of the anterior and posterior wall of the abdominal aorta, there were significant differences in the Doppler indexes of the anterior and posterior wall of the control group (P <0.05), and the anterior and posterior wall of the anomalous group of glucose tolerance The indexes of SRs, SRe and SRa were all statistically significant (P <0.05), and the changes of SRs on the anterior wall were the most obvious. ST values in the anterior and posterior wall of the group with impaired glucose tolerance decreased compared with the control group respectively. (P <0.05). The absolute values of SRs, SRe and SRa were lower than those of the control group (P <0.05) (Table 4 and 5), and the differences were statistically significant Strain rate indicators change more pronounced with SRs. Conclusion: Ultrasound strain rate imaging can be used as a method to assess the abdominal aorta elasticity in patients with impaired glucose tolerance, and provide valuable clinical information for treatment and prognosis.