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中重度慢性阻塞性肺病(慢阻肺)患者的肺功能指标能较准确地反映其最大运动能力。经多元相关统计显示最大做功量(Wmax)和最大氧耗量(VO2max)与第一秒用力呼气量(FEV1.0、CO弥散量(DLco)、残气量与肺总量之比(RV/TLC)三项的复相关系数分别达0.970和0.894。单用FEV1.0及FEV1.0合并CLco也可较好地预测患者的最大做功量和最大氧耗量,回归方程分别为Wmax(W)=0.07·FEV1.0(ml)+33(r=0.911);VO2max(ml·min-1)=0.53,FEV1.0(ml)+333.38·DLco(ml·kPa-1·min-1)-19,r=0.890。其他通气功能参数与最大做功量及最大氧耗量也显示了较高程度的相关性。而动脉血液气体分析结果(pH、PaO2、PaCO2)与运动能力之间的相关性则无显著性差异。
Pulmonary function in patients with moderate-severe chronic obstructive pulmonary disease (COPD) can more accurately reflect the maximum exercise capacity. Multivariate statistics showed that Wmax and VO2max were positively correlated with FEV1.0, DLco, RV / TLC) the three correlation coefficients were 0.970 and 0.894, respectively, combined FEV1.0 and FEV1.0 alone CLco can better predict the maximum amount of work and the maximum oxygen consumption of patients, the regression equation were Wmax (W) = 0.07 FEV1.0 (ml) +33 (r = 0.911); VO2max (ml min-1) = 0.53 FEV1.0 (ml) + 333.38 DLco · KPa-1 · min-1) -19, r = 0.890 Other parameters of ventilation function also showed a higher degree of correlation with the maximum amount of work and the maximum oxygen consumption.And arterial blood gas analysis results (pH, PaO2, PaCO2) and exercise capacity was no significant correlation Sex differences.