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最近的全基因组研究结果表明,人类基因组某些区域可能参与高血压表型的传递,高血压家族遗传参与高血压的发病。但以往研究主要涉及常染色体,迄今为止,对于性染色体在高血压家族遗传中的作用还未阐明。研究人员获取意大利那不勒斯费德里克二世大学医院高血压中心Campania Salute数据库资料,应用父系、母系遗传及性别(男、女)的二元变量对高血压患者12 504(男6868、女5636)例和对照组人群6352(男3484、女2868)名进行分析。高血压组中有
Recent genome-wide studies have shown that certain regions of the human genome may be involved in the transmission of phenotypes of hypertension and the hereditary inheritance of hypertension is involved in the pathogenesis of hypertension. However, previous studies mainly involved autosomal, so far, the role of sex chromosomes in the family history of hypertension has not been elucidated. The researchers obtained data from the Campania Salute database of the Hypertension Center of the University Hospital Federico II in Naples, Italy. Using binary variables of paternal lineage, maternal heredity and gender (male and female), 12 504 (6868 male and 5636 female) patients with hypertension And control group 6352 (male 3484, female 2868) were analyzed. There are hypertension group