论文部分内容阅读
目的探讨亚甲蓝检测宫颈癌前哨淋巴结(SLN)在盆腔淋巴清扫术中的意义。方法分析18例宫颈癌患者采用亚甲蓝检测宫颈癌SLN在腹腔镜广泛性子宫切除和盆腔淋巴结清扫术的临床资料。结果检测到至少有1枚(SLN)的有15例,检测失败3例,总检出率83.33%。蓝染的淋巴结总共27枚,占总切除淋巴结的8.33%(27/324)。每例患者检出SLN1～4枚,平均1.8枚。SLN定位于闭孔窝最常见,占40.74%(11/27),髂内33.33%(9/27),髂外18.52%(5/27),髂总3.7%(1/27),腹股沟深3.7%(1/27)。SLN的阴性预测值为100%。无过敏和感染等并发症。结论宫颈注射亚甲蓝检测宫颈癌的SLN是可行的,但其意义尚需大样本临床研究证实。
Objective To investigate the significance of methylene blue in detection of cervical cancer sentinel lymph node (SLN) in pelvic lymph node dissection. Methods The clinical data of 18 patients with cervical cancer using methylene blue to detect cervical cancer SLN in laparoscopic radical hysterectomy and pelvic lymph node dissection were analyzed. Results There were 15 cases with at least 1 SLN detected, 3 cases failed to detect, and the total detection rate was 83.33%. A total of 27 blue-stained lymph nodes, accounting for 8.33% of total resection lymph nodes (27/324). Each patient detected SLN1 ~ 4, an average of 1.8. The most common SLN was located in closed cells, accounting for 40.74% (11/27), 33.33% (9/27) in internal ilium, 18.52% (5/27) in external ilium, 3.7% (1/27) in common iliac, deep in groin 3.7% (1/27). The negative predictive value for SLN was 100%. No allergies and infections and other complications. Conclusion Cervical injection of methylene blue to detect cervical cancer SLN is feasible, but its significance still needs a large sample of clinical studies confirmed.