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探讨中国人胰腺癌的发生与阑尾切除术、胃部分切除术、胆囊切除术及扁桃体摘除术间的关系。病例对照研究以 4 93例病理确诊胰腺癌患者作为病例组 ,10 31例非肿瘤患者年龄、性别、居住地、经济收入频数匹配的同来源病例为对照组 ,计算比值比 (OR)值及95 %可信区间 (CI) ,以估计阑尾切除术、胃部分切除术、胆囊切除术及扁桃体摘除术对胰腺癌的相对危险性 ,并做logistic回归分析。结果表明在阑尾切除术、胃部分切除术、胆囊切除术者中胰腺癌的危险性上升 ,趋势检验P均 <0 0 1,OR和 95 %CI分别为 2 12 (1 4 7～ 3 0 6 )、3 11(1 4 9～ 6 5 0 )、4 71(2 4 0～ 9 5 0 ) ,而扁桃体摘除者为 2 80 (0 6 7～11 98) ,但logistic回归分析仅阑尾切除有统计学意义 (P <0 0 5 )。
To investigate the relationship between the occurrence of pancreatic cancer in Chinese and appendectomy, partial gastrectomy, cholecystectomy and tonsillectomy. The case-control study included 4 93 pathologically confirmed cases of pancreatic adenocarcinoma as the case group. The age, gender, place of residence and income of the same source matched the same source cases among 10 31 non-tumor patients as the control group, and the odds ratio (OR) and 95 % Confidence interval (CI) to estimate the relative risk of appendectomy, partial gastrectomy, cholecystectomy and tonsillectomy for pancreatic cancer, and logistic regression analysis. The results showed that in the appendectomy, partial gastrectomy, cholecystectomy, the risk of pancreatic cancer increased trend test P <0 01, OR and 95% CI were 2 12 (147 ~ 306 ), 3 11 (14 9 ~ 6 5 0), 4 71 (24 0 ~ 9 5 0), and tonsillectomy 2 80 (0 6 7 ~ 11 98). However, logistic regression analysis showed only appendectomy Statistical significance (P <0 05).