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目的观察奥曲肽在治疗上消化道大出血中的疗效。方法选择上消化大出血患者56例,随机分为2组。治疗组28例,对照组28例。治疗组:用奥曲肽0.1 mg静脉推注,再给0.6 mg加入5%葡萄糖或0.9%氯化钠500 ml中,通过输液泵以50μg/h的速度连续静脉滴注,用药3 d。对照组:用垂体后叶素10单位静推,再给予20单位加入10%葡萄糖500 ml或0.9%氯化钠持续静脉滴注20 h。用药2～3 d。结果治疗组奥曲肽止血有效率89.3%明显高于对照组的止血率71%,差异有统计学意义(P<0.05)结论奥曲肽治疗上消化道大出血疗效显著。
Objective To observe the efficacy of octreotide in the treatment of upper gastrointestinal bleeding. Methods 56 cases of upper digestive bleeding were randomly divided into two groups. 28 cases in the treatment group and 28 cases in the control group. Treatment group: intravenous injection of octreotide 0.1 mg, then 0.6 mg added 5% glucose or 0.9% sodium chloride 500 ml, by infusion pump 50μg / h continuous intravenous infusion, medication 3 d. Control group: 10 units of pituitrin static push, and then given 20 units by adding 10% glucose 500 ml or 0.9% sodium chloride continuous infusion of 20 h. Medication 2 ~ 3 d. Results In the treatment group, the effective rate of octreotide hemostasis was 89.3%, which was significantly higher than that of the control group (71%). The difference was statistically significant (P0.05). Conclusion The effect of octreotide on upper gastrointestinal bleeding was significant.