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目的 探讨体外受精与胚胎移植 (IVF -ET)程序中注射人绒毛膜促性腺激素 (HCG)日血清雌二醇(E2 )水平及获卵数目对其治疗结局的影响。方法 回顾分析 2 0 0 0年 2月至 2 0 0 1年 1月 94 7个IVF -ET周期的资料。结果 注射HCG日血清E2 水平过高、获卵过多者 ,IVF -ET卵母细胞受精率下降 ,IVF -ET临床妊娠率从单因素分析 ,有增高趋势 ,经多因素Logistic回归分析 ,排除年龄等干扰因素后 ,血E2 水平及获卵数对IVF -ET临床妊娠的影响无统计学意义。血E2 水平过高及获卵过多者 ,伴随重度OHSS发生率的上升。结论 注射HCG日血E2 水平过高及获卵数过多不能预测IVF -ET的临床妊娠
Objective To investigate the effect of the level of serum estradiol (E2) on the day of human chorionic gonadotropin (HCG) injection and the number of oocytes retrieved during the in vitro fertilization and embryo transfer (IVF-ET) procedure. Methods The data of 94 7 IVF-ET cycles from February 2000 to January 2001 were retrospectively analyzed. Results Serum E2 level on HCG day was significantly higher than that in IVF-ET group. IVF-ET clinical pregnancy rate increased from univariate analysis. Logistic regression analysis showed that the age of IVF- After interference factors such as blood E2 levels and the number of oocytes on IVF-ET clinical pregnancy had no significant effect. Overexpression of E2 and overexpression, accompanied by an increase in the incidence of severe OHSS. Conclusions The level of E2 in HCG blood is too high and the number of oocytes retrieved can not predict the clinical pregnancy of IVF-ET