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目的探讨腹膜透析(PD)治疗婴幼儿先天性心脏病术后并发急性肾损伤(AKI)的疗效。方法回顾分析21例先天性心脏病术后AKI行PD治疗患儿的临床资料,将其分成存活组及死亡组,观察PD治疗前两组开始透析时间及治疗前后生化指标的变化。结果经PD治疗后患儿血钾、血肌酐及中心静脉压均有改善(P<0.01),死亡组开始腹膜透析时间明显延后(P<0.01)。结论 PD对婴幼儿体外循环心脏手术后AKI有较好的治疗效果,年龄及开始透析时间可影响患儿预后,尽早开始PD治疗有助于降低死亡率。
Objective To investigate the efficacy of peritoneal dialysis (PD) in the treatment of acute kidney injury (AKI) in infants with congenital heart disease. Methods The clinical data of 21 children with AKI treated with PD undergoing congenital heart disease were analyzed retrospectively. The patients were divided into survival group and death group. The dialysis duration and the biochemical indexes before and after treatment were observed before PD treatment. Results After treatment with PD, serum potassium, serum creatinine and central venous pressure were both improved (P <0.01), and peritoneal dialysis time was significantly delayed after death in PD group (P <0.01). Conclusions PD has a better therapeutic effect on AKI after cardiopulmonary bypass in infants and young children. The age and dialysis duration may affect the prognosis of children. Starting PD treatment as soon as possible may help reduce the mortality rate.