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目的观察复方丹参滴丸,血栓通注射液(有效成分为三七总皂甙)联合低分子肝素钙治疗不稳定型心绞痛的临床疗效。方法将150例患者随机分为3组,对照组采用常规治疗,丹参组在常规治疗基础上应用复方丹参滴丸,血栓通组在常规治疗的基础上,加用血栓通治疗。观察3组治疗前后心绞痛发作次数、心绞痛持续时间、发作间隔时间、24hHolter缺血总时间变化等。结果丹参组总有效率为94%,血栓通组总有效率为90%,均优于对照组的86%(P<0.05),且两治疗组在心绞痛发作次数、持续时间、发作间隔时间及24hHotter缺血总时间改善方面均优于对照组(P<0.05)。结论复方丹参滴丸、血栓通联合低分子肝素钙治疗不稳定型心绞痛疗效确切。
Objective To observe the clinical efficacy of compound Danshen Dripping Pills and Xueshuantong Injection (the active ingredient is Panax notoginseng saponins) in combination with low molecular weight heparin calcium in the treatment of unstable angina pectoris. Methods 150 patients were randomly divided into three groups. The control group was treated by conventional therapy. The Salvia miltiorrhiza group was given Fufang Danshen dripping pills on the basis of routine treatment. Xueshuantong group was treated with Xueshuantong on the basis of routine treatment. The number of angina attacks, the duration of angina pectoris, the interval of seizure and the total time of 24hHolter ischemia were observed before and after treatment. Results The total effective rate was 94% in Salvia miltiorrhiza group and 90% in Xuesaitong group, both of which were better than 86% of control group (P <0.05). The number of angina pectoris, duration, interval of seizure, 24hHotter ischemic total time improvement are better than the control group (P <0.05). Conclusion Compound Danshen Dripping Pills, Xueshuantong combined with low molecular weight heparin calcium for the treatment of unstable angina pectoris.