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目的观察探讨过氧化氢在辅助治疗产褥感染中的作用,总结其临床应用价值。方法选取我院2010年5月至2012年5月产褥感染的患者56例,按照数字表随机抽取的方法将其分成观察组和对照组,各有28例,观察组采用过氧化氢联合甲硝唑进行宫腔冲洗治疗,对照组采用传统氨苄青加青霉素治疗(针对皮试不合格患者,改用林可霉素联合庆大霉素),观察比较两组临床疗效。结果观察组治疗总有效率为96.4%(27/28),不良反应率为0;对照组治疗总有效率为78.6%(22/28),不良反应率为10.7%(3/28),两组临床疗效及不良反应率比较有明显差异(P<0.05),具有统计学意义。结论过氧化氢联合甲硝唑进行宫腔冲洗治疗产褥感染的效果满意,明显优于传统抗生素治疗,可以迅速消除或减轻临床症状,有效阻碍上行性感染,且不良反应少,安全性较高,值得临床合理推广并使用。
Objective To investigate the role of hydrogen peroxide in the treatment of puerperal infection and to summarize its clinical value. Methods Fifty-six patients with puerperal infection in our hospital from May 2010 to May 2012 were randomly divided into observation group and control group according to the digital table. Each group had 28 cases. The observation group was treated with hydrogen peroxide combined with a Treatment of patients with uterine cavity was treated with nidazole, and the control group was treated with traditional ampicillin and penicillin (Lincomycin combined with gentamicin was used instead of skin test), and the clinical efficacy was observed and compared between the two groups. Results The total effective rate of the observation group was 96.4% (27/28), the rate of adverse reactions was 0. The total effective rate of the control group was 78.6% (22/28) and the adverse reaction rate was 10.7% (3/28) The clinical efficacy and adverse reaction rate were significantly different (P <0.05), with statistical significance. Conclusions Hydrogen peroxide combined with metronidazole for uterine flushing is effective in treating puerperal infection, which is obviously superior to traditional antibiotic treatment, which can quickly eliminate or relieve clinical symptoms, effectively hinder the upward infection, and have fewer adverse reactions and higher safety , It is worth clinical promotion and use.