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对２８例顽固性癫痫病例的病灶定位、手术方式、术后疗效几方面进行分析总结。方法对２８例病史在３ａ以上癫痫患者，术前进行３次以上脑电生理和ＣＴ（ＭＲＩ）检查，依照检查结果选择手术方式，术中在皮层脑电监测下将癫痫（病）灶切除。结果依Ｗｉｌｉａｓｏｎ疗效评定标准总有效率９２．８％（２６／２８）。结论治疗效果主要取决于术前、术中致痫灶的精确定位。正确的选择手术方式则是预防并发症的关键。只有借助脑电生理、ＣＴ（ＭＲＩ）等手段反复检查，才能最大限度地提高定位精确度，取得良好的治疗效果。
Twenty-eight patients with refractory epilepsy were retrospectively analyzed in the aspects of lesion location, operation method and postoperative efficacy. Methods 28 cases of epilepsy patients with a history of more than 3a were examined with electroencephalography (EEG) and CT (MRI) three times before surgery. The surgical procedures were selected according to the results of the examination. The intracerebral epilepsy was excised under the monitoring of cortical EEG. The results according to Wiliason curative effect evaluation standard total effective rate 92.8% (26/28). Conclusion The therapeutic effect mainly depends on the precise location of the epileptogenic focus in preoperative and intraoperative. Correct choice of surgical approach is the key to preventing complications. Only by means of brain electrophysiology, CT (MRI) and other means repeatedly check in order to maximize the positioning accuracy and achieve good therapeutic effect.