胺碘酮与利多卡因治疗急性心肌梗死并室性心律失常疗效比较

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目的:比较胺碘酮与利多卡因治疗急性心肌梗死并室性心律失常的临床疗效。方法:选择佛山市顺德区新容奇医院2014年7月至2015年7月收治的96例急性心肌梗死并室性心律失常患者为研究对象,按照随机数字表法分成观察组和对照组,对照组采用利多卡因治疗,观察组采用胺碘酮治疗,治疗1周后,对两组患者临床疗效和不良反应进行比较。结果:观察组总有效率为95.8%,显著高于对照组81.3%,组间比较,差异具有统计学意义(P<0.05);观察组不良反应发生率为4.2%,显著低于对照组22.9%,组间比较,差异具有统计学意义(P<0.05)。结论:采用胺碘酮治疗急性心肌梗死并室性心律失常,其临床疗效和药物安全性均显著高于利多卡因。 Objective: To compare the clinical efficacy of amiodarone and lidocaine in the treatment of acute myocardial infarction with ventricular arrhythmia. Methods: A total of 96 acute myocardial infarction patients with ventricular arrhythmia admitted from July 2014 to July 2015 in Xin Rong Qi Hospital of Shunde District of Foshan City were enrolled in this study. The patients were divided into observation group and control group according to random number table Group treated with lidocaine, observation group treated with amiodarone, after 1 week of treatment, the clinical efficacy and adverse reactions were compared between the two groups. Results: The total effective rate in the observation group was 95.8%, which was significantly higher than that in the control group (81.3%). The differences between the two groups were statistically significant (P <0.05). The adverse reaction rate in the observation group was 4.2%, significantly lower than that in the control group %, Compared between groups, the difference was statistically significant (P <0.05). Conclusion: Amiodarone in the treatment of acute myocardial infarction with ventricular arrhythmia, its clinical efficacy and drug safety were significantly higher than lidocaine.
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